Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales

Pre-existing and de novo genetic variants can both drive adaptation to environmental changes, but their relative contributions and interplay remain poorly understood. Here we investigated the evolutionary dynamics in drug-treated yeast populations with different levels of pre-existing variation by e...

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Veröffentlicht in:Mol Biol Evol
Hauptverfasser: Li, Jing, Vázquez-García, Ignacio, Persson, Karl, González, Asier, Yue, Jia-Xing, Barré, Benjamin, Hall, Michael N, Long, Anthony, Warringer, Jonas, Mustonen, Ville, Liti, Gianni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Discoveries
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445301/
https://ncbi.nlm.nih.gov/pubmed/30657986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz006
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