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Considerations and challenges in studying liquid-liquid phase separation and biomolecular condensates

Evidence is now mounting that liquid-liquid phase separation (LLPS) underlies the formation of membraneless compartments in cells. This realization has motivated major efforts to delineate the function of such biomolecular condensates in normal cells and their roles in contexts ranging from developm...

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Dettagli Bibliografici
Pubblicato in:Cell
Autori principali: Alberti, Simon, Gladfelter, Amy, Mittag, Tanja
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445271/
https://ncbi.nlm.nih.gov/pubmed/30682370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.12.035
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