SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism

BACKGROUND: SIRT4, a protein localized in the mitochondria, is one of the least characteristic members of the sirtuin family. It is known that SIRT4 has deacetylase activity and plays a role in energy metabolism, but little is known about its possible role in carcinogenesis. Recently, several studie...

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Publicat a:Onco Targets Ther
Autors principals: Chen, Zhouxun, Lin, Jiahao, Feng, Shuyi, Chen, Xuxu, Huang, Hanzhang, Wang, Chen, Yu, Yujun, He, Yu, Han, Shaoliang, Zheng, Linfeng, Huang, Guoyu
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445187/
https://ncbi.nlm.nih.gov/pubmed/30992675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S189536
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