Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic Thyroid Cancer

Malignant human anaplastic thyroid cancer (ATC) is pertinacious to conventional therapies. The present study investigated the anti-cancer activity of simvastatin and its underlying regulatory mechanism in cultured ATC cells. Simvastatin (0–20 μM) concentration-dependently reduced cell viability and...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, Mei-Chieh, Tsai, Yuan-Chin, Tseng, Jen-Ho, Liou, Jr-Jiun, Horng, Steve, Wen, Heng-Ching, Fan, Yu-Ching, Zhong, Wen-Bin, Hsu, Sung-Po
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751292/
https://ncbi.nlm.nih.gov/pubmed/29236027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18122690
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