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Oxidation destabilizes toxic amyloid beta peptide aggregation

The aggregation of insoluble amyloid beta (Aβ) peptides in the brain is known to trigger the onset of neurodegenerative diseases, such as Alzheimer’s disease. In spite of the massive number of investigations, the underlying mechanisms to destabilize the Aβ aggregates are still poorly understood. Som...

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Publicat a:Sci Rep
Autors principals: Razzokov, J., Yusupov, M., Bogaerts, A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445117/
https://ncbi.nlm.nih.gov/pubmed/30940901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41931-6
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