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Characterisation of peripheral and central components of the rat monoiodoacetate model of Osteoarthritis

OBJECTIVE: Pain is the main reason patients report Osteoarthritis (OA), yet current analgesics remain relatively ineffective. This study investigated both peripheral and central mechanisms that lead to the development of OA associated chronic pain. DESIGN: The monoiodoacetate (MIA) model of OA was i...

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Pubblicato in:Osteoarthritis Cartilage
Autori principali: Lockwood, S.M., Lopes, D.M., McMahon, S.B., Dickenson, A.H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: W.B. Saunders For The Osteoarthritis Research Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444078/
https://ncbi.nlm.nih.gov/pubmed/30611904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2018.12.017
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