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Characterisation of peripheral and central components of the rat monoiodoacetate model of Osteoarthritis

OBJECTIVE: Pain is the main reason patients report Osteoarthritis (OA), yet current analgesics remain relatively ineffective. This study investigated both peripheral and central mechanisms that lead to the development of OA associated chronic pain. DESIGN: The monoiodoacetate (MIA) model of OA was i...

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Publicado en:Osteoarthritis Cartilage
Main Authors: Lockwood, S.M., Lopes, D.M., McMahon, S.B., Dickenson, A.H.
Formato: Artigo
Idioma:Inglês
Publicado: W.B. Saunders For The Osteoarthritis Research Society 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444078/
https://ncbi.nlm.nih.gov/pubmed/30611904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2018.12.017
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