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Designing and Characterization of a Novel Delivery System for Improved Cellular Uptake by Brain Using Dendronised Apo-E-Derived Peptide

Neurodegenerative diseases (ND) are characterized by the progressive loss of neuronal structure or function mostly associated with neuronal death. The presence of the blood–brain barrier (BBB) is considered the main obstacle that prevents the penetration of almost all drugs rendering the diseases un...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Al-azzawi, Shafq, Masheta, Dhafir, Guildford, Anna, Phillips, Gary, Santin, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443832/
https://ncbi.nlm.nih.gov/pubmed/30972332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00049
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