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Dendrimeric Poly(Epsilon-Lysine) Delivery Systems for the Enhanced Permeability of Flurbiprofen across the Blood-Brain Barrier in Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive brain disorder and age-related disease characterised by abnormal accumulation of β-amyloid (Aβ). The development of drugs to combat AD is hampered by the lack of therapeutically-active molecules able to cross the blood-brain barrier (BBB). It is agreed that...

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Publicat a:Int J Mol Sci
Autors principals: Al-azzawi, Shafq, Masheta, Dhafir, Guildford, Anna L., Phillips, Gary, Santin, Matteo
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214014/
https://ncbi.nlm.nih.gov/pubmed/30340406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103224
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