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Loss of fibrinogen in zebrafish results in an asymptomatic embryonic hemostatic defect and synthetic lethality with thrombocytopenia

BACKGROUND: Mutations in the alpha chain of fibrinogen (FGA), like deficiencies in other fibrinogen subunits, lead to rare inherited autosomal recessive hemostatic disorders. These range from asymptomatic to catastrophic life-threatening bleeds, and the molecular basis of inherited fibrinogen defici...

詳細記述

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書誌詳細
出版年:J Thromb Haemost
主要な著者: Hu, Z., Lavik, K. I., Liu, Y., Vo, A. H., Richter, C. E., Paola, J. Di, Shavit, J. A.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443434/
https://ncbi.nlm.nih.gov/pubmed/30663848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14391
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