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Loss of fibrinogen in zebrafish results in an asymptomatic embryonic hemostatic defect and synthetic lethality with thrombocytopenia
BACKGROUND: Mutations in the alpha chain of fibrinogen (FGA), like deficiencies in other fibrinogen subunits, lead to rare inherited autosomal recessive hemostatic disorders. These range from asymptomatic to catastrophic life-threatening bleeds, and the molecular basis of inherited fibrinogen defici...
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| Publicado no: | J Thromb Haemost |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443434/ https://ncbi.nlm.nih.gov/pubmed/30663848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14391 |
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