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Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides
Sactipeptides are ribosomally-synthesized peptides that contain a characteristic thioether bridge (sactionine bond) that is installed posttranslationally and is absolutely required for their antibiotic activity. Sactipeptide biosynthesis requires a unique family of radical SAM enzymes, which contain...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443407/ https://ncbi.nlm.nih.gov/pubmed/28704043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01283 |
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