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OAS1 and OAS3 negatively regulate the expression of chemokines and interferon-responsive genes in human macrophages
Upon viral infection, the 2′, 5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNaseL) system works to cleave viral RNA, thereby blocking viral replication. However, it is unclear whether OAS proteins have a role in regulating gene expression. Here, we show that OAS1 and OAS3 act as negative regul...
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| Publicado no: | BMB Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443328/ https://ncbi.nlm.nih.gov/pubmed/30078389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2019.52.2.129 |
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