Psoralen-loaded lipid-polymer hybrid nanoparticles enhance doxorubicin efficacy in multidrug-resistant HepG2 cells

BACKGROUND: Psoralen (PSO), a major active component of Psoralea corylifolia, has been shown to overcome multidrug resistance in cancer. A drug carrier comprising a lipid-monolayer shell and a biodegradable polymer core for sustained delivery and improved efficacy of drug have exhibited great potent...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Autores principales: Yuan, Yueling, Cai, Tiange, Callaghan, Richard, Li, Qianwen, Huang, Yinghong, Wang, Bingyue, Huang, Qingqing, Du, Manling, Ma, Qianqian, Chiba, Peter, Cai, Yu
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443224/
https://ncbi.nlm.nih.gov/pubmed/30988617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S189924
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