Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells

AIM: To investigate the role of Beclin 1 on the susceptibility of HepG2 cells to undergo apoptosis after anti-Fas antibody or doxorubicin treatment. METHODS: Beclin 1 silencing was achieved using RNA interference. DNA ploidy, the percentage of apoptotic cells and the mitochondrial membrane potential...

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Detaylı Bibliyografya
Asıl Yazarlar: Daniel, Fanny, Legrand, Agnès, Pessayre, Dominique, Vadrot, Nathalie, Descatoire, Véronique, Bernuau, Dominique
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Baishideng Publishing Group Co., Limited 2006
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087807/
https://ncbi.nlm.nih.gov/pubmed/16718815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i18.2895
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