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Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells
AIM: To investigate the role of Beclin 1 on the susceptibility of HepG2 cells to undergo apoptosis after anti-Fas antibody or doxorubicin treatment. METHODS: Beclin 1 silencing was achieved using RNA interference. DNA ploidy, the percentage of apoptotic cells and the mitochondrial membrane potential...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Co., Limited
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4087807/ https://ncbi.nlm.nih.gov/pubmed/16718815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i18.2895 |
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