Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma

Constitutive activation of the chemokine receptor CXCR4 has been associated with tumor progression, invasion, and chemotherapy resistance in different cancer subtypes. Although the CXCR4 pathway has recently been suggested as an adverse prognostic marker in diffuse large B-cell lymphoma, its biologi...

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Vydáno v:Haematologica
Hlavní autoři: Recasens-Zorzo, Clara, Cardesa-Salzmann, Teresa, Petazzi, Paolo, Ros-Blanco, Laia, Esteve-Arenys, Anna, Clot, Guillem, Guerrero-Hernández, Martina, Rodríguez, Vanina, Soldini, Davide, Valera, Alexandra, Moros, Alexandra, Climent, Fina, González-Barca, Eva, Mercadal, Santiago, Arenillas, Leonor, Calvo, Xavier, Mate, José Luís, Gutiérrez-García, Gonzalo, Casanova, Isolda, Mangues, Ramón, Sanjuan-Pla, Alejandra, Bueno, Clara, Menéndez, Pablo, Martínez, Antonio, Colomer, Dolors, Tejedor, Roger Estrada, Teixidó, Jordi, Campo, Elias, López-Guillermo, Armando, Borrell, José Ignacio, Colomo, Luis, Pérez-Galán, Patricia, Roué, Gaël
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442946/
https://ncbi.nlm.nih.gov/pubmed/29954928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.180505
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