Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3

Mitochondria generate most cellular energy and are targeted by multiple pathogens during infection. In turn, metazoans employ surveillance mechanisms such as the mitochondrial unfolded protein response (UPR(mt)) to detect and respond to mitochondrial dysfunction as an indicator of infection. The UPR...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Deng, Pan, Uma Naresh, Nandhitha, Du, Yunguang, Lamech, Lilian T., Yu, Jun, Zhu, Lihua Julie, Pukkila-Worley, Read, Haynes, Cole M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442607/
https://ncbi.nlm.nih.gov/pubmed/30850535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817259116
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