Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3

Mitochondria generate most cellular energy and are targeted by multiple pathogens during infection. In turn, metazoans employ surveillance mechanisms such as the mitochondrial unfolded protein response (UPR(mt)) to detect and respond to mitochondrial dysfunction as an indicator of infection. The UPR...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Deng, Pan, Uma Naresh, Nandhitha, Du, Yunguang, Lamech, Lilian T., Yu, Jun, Zhu, Lihua Julie, Pukkila-Worley, Read, Haynes, Cole M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442607/
https://ncbi.nlm.nih.gov/pubmed/30850535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817259116
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