Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3

Mitochondria generate most cellular energy and are targeted by multiple pathogens during infection. In turn, metazoans employ surveillance mechanisms such as the mitochondrial unfolded protein response (UPR(mt)) to detect and respond to mitochondrial dysfunction as an indicator of infection. The UPR...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Deng, Pan, Uma Naresh, Nandhitha, Du, Yunguang, Lamech, Lilian T., Yu, Jun, Zhu, Lihua Julie, Pukkila-Worley, Read, Haynes, Cole M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442607/
https://ncbi.nlm.nih.gov/pubmed/30850535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817259116
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