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Global analysis of methionine oxidation provides a census of folding stabilities for the human proteome

The stability of proteins influences their tendency to aggregate, undergo degradation, or become modified in cells. Despite their significance to understanding protein folding and function, quantitative analyses of thermodynamic stabilities have been mostly limited to soluble proteins in purified sy...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Walker, Ethan J., Bettinger, John Q., Welle, Kevin A., Hryhorenko, Jennifer R., Ghaemmaghami, Sina
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442572/
https://ncbi.nlm.nih.gov/pubmed/30846556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819851116
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