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Global analysis of methionine oxidation provides a census of folding stabilities for the human proteome

The stability of proteins influences their tendency to aggregate, undergo degradation, or become modified in cells. Despite their significance to understanding protein folding and function, quantitative analyses of thermodynamic stabilities have been mostly limited to soluble proteins in purified sy...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Walker, Ethan J., Bettinger, John Q., Welle, Kevin A., Hryhorenko, Jennifer R., Ghaemmaghami, Sina
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442572/
https://ncbi.nlm.nih.gov/pubmed/30846556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819851116
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