Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma

BACKGROUND: Glioma is a common brain tumor with a high mortality rate. A small population of cells expressing stem-like cell markers in glioma contributes to drug resistance and tumor recurrence. METHODS: Porous silicon nanoparticles (PSi NPs) as photothermal therapy (PTT) agents loaded with TMZ (TM...

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Dettagli Bibliografici
Pubblicato in:J Nanobiotechnology
Autori principali: Zeng, Xiaofan, Wang, Qi, Tan, Xuan, Jia, Le, Li, Yuwei, Hu, Mingdi, Zhang, Zhijie, Bai, Xicheng, Zhu, Yanhong, Yang, Xiangliang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442425/
https://ncbi.nlm.nih.gov/pubmed/30935403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0483-1
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