Long-read single-molecule maps of the functional methylome

We report on the development of a methylation analysis workflow for optical detection of fluorescent methylation profiles along chromosomal DNA molecules. In combination with Bionano Genomics genome mapping technology, these profiles provide a hybrid genetic/epigenetic genome-wide map composed of DN...

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Publié dans:Genome Res
Auteurs principaux: Sharim, Hila, Grunwald, Assaf, Gabrieli, Tslil, Michaeli, Yael, Margalit, Sapir, Torchinsky, Dmitry, Arielly, Rani, Nifker, Gil, Juhasz, Matyas, Gularek, Felix, Almalvez, Miguel, Dufault, Brandon, Chandra, Sreetama Sen, Liu, Alexander, Bhattacharya, Surajit, Chen, Yi-Wen, Vilain, Eric, Wagner, Kathryn R., Pevsner, Jonathan, Reifenberger, Jeff, Lam, Ernest T., Hastie, Alex R., Cao, Han, Barseghyan, Hayk, Weinhold, Elmar, Ebenstein, Yuval
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2019
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Method
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442387/
https://ncbi.nlm.nih.gov/pubmed/30846530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.240739.118
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