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Cohesin occupancy and composition at enhancers and promoters are linked to DNA replication origin proximity in Drosophila

Cohesin consists of the SMC1-SMC3-Rad21 tripartite ring and the SA protein that interacts with Rad21. The Nipped-B protein loads cohesin topologically around chromosomes to mediate sister chromatid cohesion and facilitate long-range control of gene transcription. It is largely unknown how Nipped-B a...

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Опубликовано в: :Genome Res
Главные авторы: Pherson, Michelle, Misulovin, Ziva, Gause, Maria, Dorsett, Dale
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442380/
https://ncbi.nlm.nih.gov/pubmed/30796039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.243832.118
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