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DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development
BACKGROUND: Cytosine methylation of regulatory regions, such as promoters and enhancers, plays a key role in regulating gene expression, however, its role in kidney development has not been analyzed. METHODS: To identify functionally important epigenome-modifying enzymes and genome regions where met...
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| Publié dans: | J Am Soc Nephrol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Nephrology
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442333/ https://ncbi.nlm.nih.gov/pubmed/30850438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018070687 |
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