Isoprenylcysteine carboxy methyltransferase (ICMT) is associated with tumor aggressiveness and its expression is controlled by the p53 tumor suppressor

Isoprenyl cysteine carboxyl methyltransferase (ICMT) plays a key role in post-translational regulation of prenylated proteins. On the basis of previous results, we hypothesized that the p53 pathway and ICMT expression may be linked in cancer cells. Here, we studied whether WT p53 and cancer-associat...

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Publicat a:J Biol Chem
Autors principals: Borini Etichetti, Carla, Di Benedetto, Carolina, Rossi, Carolina, Baglioni, María Virginia, Bicciato, Silvio, Del Sal, Giannino, Menacho-Marquez, Mauricio, Girardini, Javier
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442035/
https://ncbi.nlm.nih.gov/pubmed/30655292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006037
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