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Evolution of Antigenic Variation in African Trypanosomes: Variant Surface Glycoprotein Expression, Structure, and Function

The process of antigenic variation in parasitic African trypanosomes is a remarkable mechanism for outwitting the immune system of the mammalian host, but it requires a delicate balancing act for the monoallelic expression, folding and transport of a single variant surface glycoprotein (VSG). Only o...

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Detalhes bibliográficos
Publicado no:Bioessays
Autor principal: Bangs, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441954/
https://ncbi.nlm.nih.gov/pubmed/30370931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201800181
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