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Variant surface glycoprotein density defines an immune evasion threshold for African trypanosomes undergoing antigenic variation

Trypanosoma brucei is a protozoan parasite that evades its host’s adaptive immune response by repeatedly replacing its dense variant surface glycoprotein (VSG) coat from its large genomic VSG repertoire. While the mechanisms regulating VSG gene expression and diversification have been examined exten...

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Foilsithe in:Nat Commun
Main Authors: Pinger, Jason, Chowdhury, Shanin, Papavasiliou, F. Nina
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635023/
https://ncbi.nlm.nih.gov/pubmed/29018220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00959-w
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