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Role of Na(V)1.6 and Na(V)β4 sodium channel subunits in a rat model of low back pain induced by compression of the dorsal root ganglia

Low back pain is a common cause of chronic pain and disability. It is modeled in rodents by chronically compressing the lumbar dorsal root ganglia (DRG) with small metal rods, resulting in ipsilateral mechanical and cold hypersensitivity, and hyperexcitability of sensory neurons. Sodium channels are...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Xie, Wenrui, Zhang, Jingdong, Strong, Judith A., Zhang, Jun-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441841/
https://ncbi.nlm.nih.gov/pubmed/30699332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.01.012
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