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Knockdown of sodium channel Na(V)1.6 blocks mechanical pain and abnormal bursting activity of afferent neurons in inflamed sensory ganglia
Inflammatory processes in the sensory ganglia contribute to many forms of chronic pain. We previously showed that local inflammation of the lumbar sensory ganglia rapidly leads to prolonged mechanical pain behaviors and high levels of spontaneous bursting activity in myelinated cells. Abnormal spont...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3699898/ https://ncbi.nlm.nih.gov/pubmed/23622763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.02.027 |
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