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Immunohistochemistry for Histone H3G34W and H3K36M Is Highly Specific for Giant Cell Tumor of Bone and Chondroblastoma, Respectively, in FNA and Core Needle Biopsy
BACKGROUND: Diagnosing giant cell-rich bone tumors can be challenging on limited biopsies. H3 histone family member 3A (H3F3A) (G34W/V/R/L) mutations are present in the majority of giant cell tumors (GCTs) of bone and H3 histone family member 3B (H3F3B) (K36M) mutations are present in nearly all cho...
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| Publicat a: | Cancer Cytopathol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6441393/ https://ncbi.nlm.nih.gov/pubmed/29757500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncy.22000 |
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