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Histone H3K36M Mutation and Trimethylation Patterns in Chondroblastoma

BACKGROUND: Histones are essential components of chromatin and mutations in histones lead to alterations in methylation and acetylation, which play an important role in tumorigenesis. Most of the chondroblastomas harbor H3K36M mutation. With the availability of mutation specific antibody, we aimed t...

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Библиографические подробности
Опубликовано в: :Histopathology
Главные авторы: Lu, Chuanyong, Ramirez, Daniel, Hwang, Sinchun, Jungbluth, Achim, Frosina, Denise, Ntiamoah, Peter, Healey, John, Zhu, Guo, Chen, Wen, Klein, Michael, Hameed, Meera
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298805/
https://ncbi.nlm.nih.gov/pubmed/30098026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/his.13725
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