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Histone H3K36M Mutation and Trimethylation Patterns in Chondroblastoma

BACKGROUND: Histones are essential components of chromatin and mutations in histones lead to alterations in methylation and acetylation, which play an important role in tumorigenesis. Most of the chondroblastomas harbor H3K36M mutation. With the availability of mutation specific antibody, we aimed t...

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Detalhes bibliográficos
Publicado no:Histopathology
Main Authors: Lu, Chuanyong, Ramirez, Daniel, Hwang, Sinchun, Jungbluth, Achim, Frosina, Denise, Ntiamoah, Peter, Healey, John, Zhu, Guo, Chen, Wen, Klein, Michael, Hameed, Meera
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298805/
https://ncbi.nlm.nih.gov/pubmed/30098026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/his.13725
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