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Characterization and Quantification of Highly Sulfated Glycosaminoglycan Isomers by Gated-TIMS NETD MS/MS

Glycosaminoglycans (GAGs) play vital roles in many biological processes, and are naturally present as complex mixtures of polysaccharides with tremendous structural heterogeneity, including many structural isomers. Mass spectrometric analysis of GAG isomers, in particular highly sulfated heparin (He...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Wei, Juan, Wu, Jiandong, Tang, Yang, Ridgeway, Mark E., Park, Melvin A., Costello, Catherine E., Zaia, Joseph, Lin, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441329/
https://ncbi.nlm.nih.gov/pubmed/30649866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b05283
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