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Kinetic Intermediates of Holo- and Apo-Myoglobin Studied Using HDX-TIMS-MS and Molecular Dynamic Simulations

[Image: see text] In the present work, the kinetic intermediates of holo- and apomyoglobin were studied by correlating the ion-neutral collision cross section and time resolved H/D back exchange rate simultaneously in a trapped ion mobility spectrometer coupled to a mass spectrometer (HDX-TIMS-MS)....

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Schenk, Emily R., Almeida, Raybel, Miksovska, Jaroslava, Ridgeway, Mark E., Park, Melvin A., Fernandez-Lima, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402236/
https://ncbi.nlm.nih.gov/pubmed/25690175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-014-1067-9
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