Long noncoding RNA Pvt1 regulates the immunosuppression activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) participate in tumor-elicited immunosuppression by dramatically blocking T-cell-induced antitumor responses, thereby influencing the effectiveness of cancer immunotherapies. Treatments that alter the differentiation and function of MDSCs can parti...

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Vydáno v:Mol Cancer
Hlavní autoři: Zheng, Yu, Tian, Xinyu, Wang, Tingting, Xia, Xueli, Cao, Fenghua, Tian, Jie, Xu, Ping, Ma, Jie, Xu, Huaxi, Wang, Shengjun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441229/
https://ncbi.nlm.nih.gov/pubmed/30925926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-0978-2
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