Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression

BACKGROUND: Cisplatin (CDDP) treatment is one of the most predominant chemotherapeutic strategies for patients with gastric cancer (GC). A better understanding of the mechanisms of CDDP resistance can greatly improve therapeutic efficacy in patients with GC. Circular RNAs (circRNAs) are a class of n...

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Bibliografski detalji
Izdano u:Mol Cancer
Glavni autori: Huang, Xiaoxu, Li, Zheng, Zhang, Qiang, Wang, Weizhi, Li, Bowen, Wang, Lu, Xu, Zhipeng, Zeng, Ailiang, Zhang, Xing, Zhang, Xuan, He, Zhongyuan, Li, Qiang, Sun, Guangli, Wang, Sen, Li, Qing, Wang, Linjun, Zhang, Lu, Xu, Hao, Xu, Zekuan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441201/
https://ncbi.nlm.nih.gov/pubmed/30927924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-0969-3
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