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MicroRNA-148a-3p enhances cisplatin cytotoxicity in gastric cancer through mitochondrial fission induction and cyto-protective autophagy suppression

Cisplatin (CDDP) resistance is a major clinical problem associated with poor prognosis in gastric cancer (GC) patients. In this study, we performed integrated analysis of TCGA data from microRNAs (miRNAs) expression matrix of GC patients who received CDDP-based chemotherapy with GEO dataset which co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Lett
Hauptverfasser: Li, Bowen, Wang, Weizhi, Li, Zheng, Chen, Zheng, Zhi, Xiaofei, Xu, Jianghao, Li, Qing, Wang, Lu, Huang, Xiaoxu, Wang, Linjun, Wei, Song, Sun, Guangli, Zhang, Xuan, He, Zhongyuan, Zhang, Lu, Zhang, Diancai, Xu, Hao, El-Rifai, Wael, Xu, Zekuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675767/
https://ncbi.nlm.nih.gov/pubmed/28965855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.09.035
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