Specialized dendritic cells induce tumor-promoting IL-10(+)IL-17(+) FoxP3(neg) regulatory CD4(+) T cells in pancreatic carcinoma

The drivers and the specification of CD4(+) T cell differentiation in the tumor microenvironment and their contributions to tumor immunity or tolerance are incompletely understood. Using models of pancreatic ductal adenocarcinoma (PDA), we show that a distinct subset of tumor-infiltrating dendritic...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Barilla, Rocky M., Diskin, Brian, Caso, Raul Caso, Lee, Ki Buom, Mohan, Navyatha, Buttar, Chandan, Adam, Salma, Sekendiz, Zennur, Wang, Junjie, Salas, Ruben D., Cassini, Marcelo F., Karlen, Jason, Sundberg, Belen, Akbar, Hashem, Levchenko, Dmitry, Gakhal, Inderdeep, Gutierrez, Johana, Wang, Wei, Hundeyin, Mautin, Torres-Hernandez, Alejandro, Leinwand, Joshua, Kurz, Emma, Rossi, Juan A. Kochen, Mishra, Ankita, Liria, Miguel, Sanchez, Gustavo, Panta, Jyoti, Loke, P’ng, Aykut, Berk, Miller, George
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441038/
https://ncbi.nlm.nih.gov/pubmed/30926808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09416-2
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