Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc(1) complex function

Of the four separate PE biosynthetic pathways in eukaryotes, one occurs in the mitochondrial inner membrane (IM) and is executed by phosphatidylserine decarboxylase (Psd1). Deletion of Psd1 is lethal in mice and compromises mitochondrial function. We hypothesize that this reflects inefficient import...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Calzada, Elizabeth, Avery, Erica, Sam, Pingdewinde N., Modak, Arnab, Wang, Chunyan, McCaffery, J. Michael, Han, Xianlin, Alder, Nathan N., Claypool, Steven M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441012/
https://ncbi.nlm.nih.gov/pubmed/30926815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09425-1
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