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Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc(1) complex function

Of the four separate PE biosynthetic pathways in eukaryotes, one occurs in the mitochondrial inner membrane (IM) and is executed by phosphatidylserine decarboxylase (Psd1). Deletion of Psd1 is lethal in mice and compromises mitochondrial function. We hypothesize that this reflects inefficient import...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Calzada, Elizabeth, Avery, Erica, Sam, Pingdewinde N., Modak, Arnab, Wang, Chunyan, McCaffery, J. Michael, Han, Xianlin, Alder, Nathan N., Claypool, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441012/
https://ncbi.nlm.nih.gov/pubmed/30926815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09425-1
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