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Human neuroblastoma SH-SY5Y cells treated with okadaic acid express phosphorylated high molecular weight tau-immunoreactive protein species
BACKGROUND: Early stages of Alzheimer’s disease (AD) are characterized by high phosphorylation of microtubule-associated protein tau, which may result from the downregulation of protein phosphatases. NEW METHOD: In order to model phosphatase downregulation and analyze its effect on tau aggregation i...
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| Publicado en: | J Neurosci Methods |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6440880/ https://ncbi.nlm.nih.gov/pubmed/30278184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2018.09.030 |
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