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Okadaic acid induces tau phosphorylation in SH-SY5Y cells in an estrogen-preventable manner
One of the pathological hallmarks of Alzheimer’s disease (AD) is neurofibrillary tangles (NFTs), which are composed of abnormally hyperphosphorylated tau, but the mechanism of tau hyperphosphorylation in AD is still unclear. To investigate the effects of estrogens on tau phosphorylation, SH-SY5Y cel...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913890/ https://ncbi.nlm.nih.gov/pubmed/20457142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.04.074 |
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