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Oxidative stress induces transient O‐GlcNAc elevation and tau dephosphorylation in SH‐SY5Y cells

O‐linked β‐N‐acetlyglucosamine or O‐GlcNAc modification is a dynamic post‐translational modification occurring on the Ser/Thr residues of many intracellular proteins. The chronic imbalance between phosphorylation and O‐GlcNAc on tau protein is considered as one of the main hallmarks of Alzheimer...

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Bibliografski detalji
Izdano u:J Cell Mol Med
Glavni autori: Kátai, Emese, Pál, József, Poór, Viktor Soma, Purewal, Rupeena, Miseta, Attila, Nagy, Tamás
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134385/
https://ncbi.nlm.nih.gov/pubmed/27456536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12910
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