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The DILI‐sim Initiative: Insights into Hepatotoxicity Mechanisms and Biomarker Interpretation

The drug‐induced liver injury (DILI)‐sim Initiative is a public‐private partnership involving scientists from industry, academia, and the US Food and Drug Administration (FDA). The Initiative uses quantitative systems toxicology (QST) to build and refine a model (DILIsym) capable of understanding an...

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Sonraí Bibleagrafaíochta
Foilsithe in:Clin Transl Sci
Príomhúdar: Watkins, Paul B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440570/
https://ncbi.nlm.nih.gov/pubmed/30762301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12629
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