Liposomes targeted to MHC-restricted antigen improve drug delivery and antimelanoma response

PURPOSE: Melanoma is the most aggressive form of skin cancer. Chemotherapy at a late stage fails due to low accumulation in tumors, indicating the need for targeted therapy. MATERIALS AND METHODS: To increase drug uptake by tumor cells, we have targeted doxorubicin-containing liposomes using a T-cel...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Saeed, Mesha, Zalba, Sara, Seynhaeve, Ann L B, Debets, Reno, ten Hagen, Timo L M
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440454/
https://ncbi.nlm.nih.gov/pubmed/30988609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S190736
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