Enhanced Specificity and Drug Delivery in Tumors by cRGD - Anchoring Thermosensitive Liposomes

PURPOSE: To develop RGD-targeted thermosensitive liposomes with increased tumor retention, improving drug release efficiency upon mild hyperthermia (HT) in both tumor and angiogenic endothelial cells. METHODS: Standard termosensitive liposomes (TSL) and TSL containing a cyclic Arg-Gly-Asp (cRGD) pen...

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Vydáno v:Pharm Res
Hlavní autoři: Dicheva, Bilyana M., ten Hagen, Timo L. M., Seynhaeve, Ann L. B., Amin, Mohamadreza, Eggermont, Alexander M. M., Koning, Gerben A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628091/
https://ncbi.nlm.nih.gov/pubmed/26202516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1746-7
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