Pharmacokinetics, Tissue Distribution and Therapeutic Effect of Cationic Thermosensitive Liposomal Doxorubicin Upon Mild Hyperthermia

PURPOSE: To evaluate pharmacokinetic profile, biodistribution and therapeutic effect of cationic thermosensitive liposomes (CTSL) encapsulating doxorubicin (Dox) upon mild hyperthermia (HT). METHODS: Non-targeted thermosensitive liposomes (TSL) and CTSL were developed, loaded with Dox and characteri...

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Enregistré dans:
Détails bibliographiques
Publié dans:Pharm Res
Auteurs principaux: Dicheva, Bilyana M., Seynhaeve, Ann L. B., Soulie, Thomas, Eggermont, Alexander M. M., ten Hagen, Timo L. M., Koning, Gerben A.
Format: Artigo
Langue:Inglês
Publié: Springer US 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744262/
https://ncbi.nlm.nih.gov/pubmed/26518763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1815-y
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