Enhanced and controlled chromatin extraction from FFPE tissues and the application to ChIP-seq

BACKGROUND: Epigenetic dysregulation is involved in the etiology and progression of various human diseases. Formalin-fixed paraffin-embedded (FFPE) samples represent the gold standard for archiving pathology samples, and thus FFPE samples are a major resource of samples in clinical research. However...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Zhong, Jian, Ye, Zhenqing, Clark, Chad R., Lenz, Samuel W., Nguyen, Justin H., Yan, Huihuang, Robertson, Keith D., Farrugia, Gianrico, Zhang, Zhiguo, Ordog, Tamas, Lee, Jeong-Heon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440302/
https://ncbi.nlm.nih.gov/pubmed/30922218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5639-8
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