Interaction with hyaluronan matrix and miRNA cargo as contributors for in vitro potential of mesenchymal stem cell-derived extracellular vesicles in a model of human osteoarthritic synoviocytes

BACKGROUND: Osteoarthritis (OA) is the most prevalent joint disease, and to date, no options for effective tissue repair and restoration are available. With the aim of developing new therapies, the impact of mesenchymal stem cells (MSCs) has been explored, and the efficacy of MSCs started to be deci...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Stem Cell Res Ther
Main Authors: Ragni, Enrico, Perucca Orfei, Carlotta, De Luca, Paola, Lugano, Gaia, Viganò, Marco, Colombini, Alessandra, Valli, Federico, Zacchetti, Daniele, Bollati, Valentina, de Girolamo, Laura
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440078/
https://ncbi.nlm.nih.gov/pubmed/30922413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1215-z
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