Interaction with hyaluronan matrix and miRNA cargo as contributors for in vitro potential of mesenchymal stem cell-derived extracellular vesicles in a model of human osteoarthritic synoviocytes

BACKGROUND: Osteoarthritis (OA) is the most prevalent joint disease, and to date, no options for effective tissue repair and restoration are available. With the aim of developing new therapies, the impact of mesenchymal stem cells (MSCs) has been explored, and the efficacy of MSCs started to be deci...

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Dades bibliogràfiques
Publicat a:Stem Cell Res Ther
Autors principals: Ragni, Enrico, Perucca Orfei, Carlotta, De Luca, Paola, Lugano, Gaia, Viganò, Marco, Colombini, Alessandra, Valli, Federico, Zacchetti, Daniele, Bollati, Valentina, de Girolamo, Laura
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440078/
https://ncbi.nlm.nih.gov/pubmed/30922413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1215-z
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