miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the sixth leading cancer worldwide. They are typically characterized by a high incidence of local recurrence, which is the most common cause of death in HNSCC patients. TP53 is the most frequently mutated gene in HNSCC and patients carryin...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Vahabi, Mahrou, Pulito, Claudio, Sacconi, Andrea, Donzelli, Sara, D’Andrea, Marco, Manciocco, Valentina, Pellini, Raul, Paci, Paola, Sanguineti, Giuseppe, Strigari, Lidia, Spriano, Giuseppe, Muti, Paola, Pandolfi, Pier Paolo, Strano, Sabrina, Safarian, Shahrokh, Ganci, Federica, Blandino, Giovanni
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440033/
https://ncbi.nlm.nih.gov/pubmed/30925916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1119-x
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